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Klotrix is one of the most effective potassium chloride supplements
made by the pharmaceutical company named APOTHECON one of the group
companies of Bristol-Myers Squibb Co. Klotrix has Potassium Chloride
Salts as its active chemical and the drug was first approved by the
Food and Drug Administration FDA of the United States precisely on
the 22nd of May in the year 1980.
Registered and branded drug Klotrix is made available in the solid
oral dose form of Potassium Chloride which contains 750mg of
potassium chloride USP grade which is equivalent to 10 mEq of
potassium, in the film-coated wax-matrix tablet. Klotrix is proposed
to provide the restricted discharge of potassium from the matrix to
diminish the chances of developing higher localized concentrations
of potassium within the gastrointestinal tract. Klotrix is the
electrolyte refilling agent. KCl is the structural formula and
chemical name of potassium chloride.
Klotrix contains several inactive ingredients like Ethyl-cellulose,
FD&C Yellow No.6 Aluminum Lake color, Glycerin, Hydroxy-propyl
methyl-cellulose 2910, Magnesium Stearate, Povidone, Colloidal
Silicon Dioxide, Stearic Acid and Titanium Dioxide. The clinical
pharmacology of Klotrix involves: the potassium ion is the vital
intracellular cation (positively charged ions) majority of the body
tissues that participate in several significant physiological
processes that incorporate the maintenance of intracellular
tonicity, the communication of nerve impulses, the contraction of
cardiac, skeletal, and smooth muscles as well as maintaining the
normal renal functions.
The drug is indicated for use that it should be reserved for the
patients who cannot tolerate or not willing to take liquids or fizzy
potassium preparations or for patients having certain problems of
complying with such preparations merely due to the reports of
intestinal and gastric ulceration and bleeding with controlled
release potassium chloride formulations.
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